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GRANTS

The Bill & Melinda Gates Foundation is accepting applications for Round 13 of its Grand Challenges Explorations initiative, an accelerated grant program that encourages bold approaches aimed at improving the lives of the world’s poorest people. Anyone — students, scientists, entrepreneurs — with a transformative idea is invited to apply.

Initial grants of $100,000 are awarded twice a year, and successful projects have the opportunity to receive a follow-on grant of up to $1 million. The five topics for Grand Challenges Explorations Round 13 are measuring fetal and infant brain mortality, integrating community-based interventions, inciting health behaviors, diarrhea and enteric dysfunctions, and innovations for building agricultural development programs.

Since its launch in 2008, the program has funded more than nine hundred grants in over fifty countries. The program welcomes proposals from a broad spectrum of contributors and encourages cross-disciplinary approaches. The Gates Foundation and an independent group of reviewers will select the most innovative proposals, and grants will be awarded within approximately four months of the proposal submission deadline.

LINK: http://www.gatesfoundation.org/Media-Center/Press-Releases/2014/03/Bill-Melinda-Gates-Foundation-Opens-Application-Round-13-of-Grand-Challenges-Explorations

 

The PhRMA Foundation is accepting proposals for “starter grants” in support of research aimed at quantifying the benefits to society that have accrued from innovations in cancer treatment.

The grant will be awarded to candidates who establish a sound and innovative research project focused on developing a novel way of quantifying or describing the social, patient-centered, and economic benefits of innovation in cancer treatment. Relevant research goals may include developing new methods to define and measure the societal benefits from cancer care innovation. For example, this could include contributing to an understanding of value across a wider range of outputs that can be more difficult to assess, capturing heterogeneity in patient values (such as quality of life, productivity, etc.) within and among populations, and accounting for variability in value over time and its relationship to long-term aggregate clinical gains against cancer.

This award is not intended for clinical or bench research, and is focused on supporting research in the health economics and social science fields. Additionally, research results should be generalizable to the context of the United States. Proposals focused on methods are eligible; however, researchers must clearly indicate how these new methods will be used to capture patient, population, or societal outcomes and benefits.

The award consists of $100,000 for one year and is made to the university or institution on behalf of the recipient, with the understanding that the university or institution will administer the funds. The “starter” aspect of the program strives to assist individuals who are establishing careers as independent investigators with an interest in describing the benefits of cancer treatment, innovation, and progress. The funds are to be used to conduct the proposed research and provide the grantee with financial support to promote future research efforts in this field.

Individuals holding the rank of instructor, assistant professor, or investigator at the doctoral level are eligible to apply.

LINK: http://phrmafoundation.org/download/Starter%20Grant.pdf

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Microscopy job opportunities

Microscopist, Electron Microscopy Laboratory,University of Reading,Reading, UK

https://www.reading.ac.uk/about/jobs/tlive_webrecruitment/wrd/run/etrec106gf.display_srch_all?wvid=9493791XsD(search Job Ref: TS14002)

FACS and Microscopy Specialist,

New Department of Systems and Synthetic Microbiology at the Max Planck Institute for Terrestrial Microbiology, Germany

http://www.eurmicsoc.org/job-offer-pdf/FACS_Microscopy_SYNMIKRO_MPI_Marburg_DE.pdf

 Light Microscopy Officer,

MRC Laboratory for Molecular Cell Biology, University College London, UK

https://atsv7.wcn.co.uk/search_engine/jobs.cgi?owner=5041178&ownertype=fair&jcode=1405755

Sales Specialist, Quorum Technologies, Laughton, East Sussex, UK

http://www.eurmicsoc.org/job-offer-pdf/Sales_speialist_job_description_060314_Quorum_Laughton_UK.pdf

Postdoc positions, International Iberian Nanotechnology Laboratory (INL), Braga, Portugal

http://www.eurmicsoc.org/job-offer-pdf/Postdoc-positions_INL_March2014_Braga_PT.pdf

http://www.eurmicsoc.org/job-offer-pdf/Postdoc-positions_INL_March2014_Braga_PT.pdf

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Call for Applications: Ovarian Cancer Research Fund Woman to Woman Program Grant

 

A Woman to Woman program grant recipient will receive a one-year grant of no more than $50,000. This grant opportunity is available to any medical institutions with a sufficient volume of gynecologic cancer patients and a need to provide this type of support service to patients. Grants are provided to cover the cost of a part-time Program Coordinator’s salary (can be a new hire, or a reassignment), program costs, and the patient fund (no indirect costs are allowed). It is expected that each Woman to Woman program will become self-funding after the first year.

OCRF will provide all program materials for patients, as well as technical assistance and support, for the life of the program (even after the end of the grant period). Programs will also have access to a dedicated section of the fund’s website available to participants only, which will feature tools to assist in the development and administration of new programs.

OCRF is now accepting applications for a Woman to Woman program grant. The deadline for submission is May 1, 2014.

For questions about Woman to Woman, please email Julia Volpin at womantowoman@ocrf.org.

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the Big C competition

Call for Applications: Livestrong Foundation Big C Competition

We’re looking for big thinkers to create tangible innovations and solutions improving the daily lives of people facing cancer.

The Big C competition is an opportunity to change the way the world fights cancer.

How it Work

Register!

May 15 deadline for submitting your product, service or innovation.

150 semi-finalists have access to mentoring, crowdfunding and media exposure.

$25,000

Five teams pitch in Austin for a chance to win $25,000!

(60 teams win a total of $140,000)

Solutions We Seek

The Big C competition invites you to submit projects addressing the following needs.

Rebuild Financial Health

Regain Emotional Wellbeing

Care for Caregivers

Improve Access to Quality Care

Fill the Knowledge Gap

Help Anyone Facing Cancer Now

link: http://www.bigc.livestrong.org/#/home

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Postdoctoral Research Fellow in Super-resolution imaging

Postdoctoral Research Fellow in Super-resolution imaging
University of Leeds -Biological Sciences

Fixed term for 54 months

Applications are invited for an experienced Postdoctoral Research Fellow to work on a project to build a novel ‘super-resolution’ 3D structured illumination microscope. The project is funded by the MRC Next Generation Optical Imaging Initiative.

You should have a PhD (or are close to completion) in an area of biophysics, physics, biochemistry or bioengineering (or related), you will use your knowledge and ability to build a novel ‘instant’ structured illumination microscopy set-up primarily to image live cells. You will also be responsible for developing and maintaining an existing PALM (photoactivated light microscopy) and STORM (stochastic optical reconstruction microscopy) set-up. You should have experience in optics, lasers, microscopy, imaging, camera technologies, programming and in building custom-built instrumentation and a strong interest in biology. The final goal is to build a novel 3D SIM instrument that can image to high resolution, with minimal drift, low signal/noise, and be relatively straightforward for other non-expert users to use. You will be creative, a quick-learner and able to work with custom-made instrumentation and non-standard analysis tools, in an interdisciplinary environment.

You should have a strong biophysical science background and experience of multidisciplinary research at the interface with biology is desirable.

University Grade 7 (£30,728 – £36,661 p.a.) Due to funding limitations it is unlikely an appointment will be made above £30,728 p.a.

Informal enquiries may be made to Professor Michelle Peckham, tel +44 (0)113 343 3438, email m.peckham@leeds.ac.uk.

Closing Date: 20 March 2014
(Redeployment Closing Date: 6 March 2014)

link: http://www.leeds.ac.uk/info/20025/university_jobs

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PhD PhD

PhD Studentship in Molecular and Cellular Evaluation of Biomarkers of Response to Therapy in Rectal Cancer Patients
Barts and The London -Centre for Digestive Diseases Blizard Institute of Cell and Molecular Science (BICMS)

Project Title: Molecular and cellular evaluation of biomarkers of response to therapy in rectal cancer patients

Supervisor: Professor Andrew Silver Co-Supervisor: Dr Cleo Bishop

Applications are invited from Biology/Biochemistry graduates with a BSc (First or Upper Second) or MSc (Distinction or Merit). Previous research experience would be an advantage This 3 year studentship will commence in July 2014 and the applicant will be based in the School’s Whitechapel Campus

This project aims to identify new biomarkers to distinguish rectal cancers likely to be refractory to neoadjuvant therapy, thereby sparing these patients unnecessary treatment and associated morbidity. The study may also uncover novel targets more suitable for therapy in patients unresponsive to current therapies. One particular feature of rectal cancer that can limit treatment success is hypoxia. We have linked hypoxic changes in rectal cancer cells to alterations in the expression key microRNAs, metabolites and pivotal members of the NADPH oxidase gene family. This multidisciplinary studentship will investigate the molecular mechanisms behind these changes and assess the utility of biomarkers of hypoxia and treatment response in patients. The project will involve collaboration with Dr Ricky Sharma, Department of Oncology, University of Oxford and there will be an opportunity to spend time in Dr Sharma’s laboratory.

The project will provide training in a range of molecular and cellular techniques and involve interaction with clinical and scientific colleagues in a highly collaborative and friendly environment. There will be access to a wide variety of cutting-edge technologies and state-of-the-are core facilities, as well as interaction with leading international researchers across a wide range of biomedical disciplines. Training will also be given in a number of transferable skills.

Informal enquires to Professor Andrew Silver (a.r.silver@qmul.ac.uk) or Dr Cleo Bishop (c.l.bishop@qmul.ac.uk)

This Studentship is sponsored by the Constance Travis Charitable Trust and comes with a minimum tax free stipend of £15,726.00 per annum. It is open to UK Nationals, EEA/Swiss migrant workers and non-UK nationals with indefinite leave to remain in the UK who all have three years ordinary residence in the UK prior to the start of the studentship.

Closing date for applications is 31st March 2014.

LINK: http://www.jobs.ac.uk/job/AIB419/phd-studentship-in-molecular-and-cellular-evaluation-of-biomarkers-of-response-to-therapy-in-rectal-cancer-patients/

PhD Studentship in Skin Immune Cell Interactions in Health and Disease
The University of Manchester -Manchester Collaborative Centre for Inflammation Research

Professor Tracy Hussell and Dr Amy Saunders

The Manchester Collaborative Centre for Inflammation Research (MCCIR) invites applications for a 3-year funded PhD due to commence October 2014. The studentship covers UK/EU tuition fees, research expenses and annual tax-free stipend of £17,000. The studentship is open to UK/EU nationals only due to the nature of the award.

The skin is one of the largest organs in the body and functions as a barrier to prevent the loss of substances and to prevent infection. To fulfil this role the skin harbours a wide range of immune cells poised to combat any invading pathogens. The lung and gut are other barrier sites and have been the focus of study for many immunologists in recent years yet surprisingly little is known about the skin immune system particularly in healthy individuals. We have recently identified that in the lung the default state of innate immune cells is to be actively restrained by signals from healthy tissue (Snelgrove, 2011) but as yet, there are little data in skin.Psoriasis is a highly prevalent inflammatory skin disease in which a wide range of immune cells are implicated (Griffiths, 2003; Griffiths, 2006). However, prior research has not focussed on cell to cell interactions. This project addresses the hypothesis that psoriasis is maintained due to a lack of regulatory mechanisms usually present in health. The PhD will analyse the contribution of these regulatory pathways to psoriasis in human skin explants and the mechanisms involved will also be explored using murine models. Training offers the opportunity to work on clinically relevant human disease and will include techniques such as flow cytometry, quantitative PCR, histology, murine models of inflammatory skin disease and human explant cultures.

This project will be hosted within the MCCIR. MCCIR is a partnership between the University of Manchester, AstraZeneca and GSK, allowing the successful applicant to gain an insight into applied research in industry. Ideal candidates will have a strong interest in immunology/dermatology and hold relevant laboratory experience.

Candidates are expected to hold a minimum upper-second (or equivalent) undergraduate degree in a relevant biological/medical science area such as immunology, dermatology and/or biochemistry. They must also have some prior laboratory experience, ideally involving some of the techniques to be employed in this project. A Masters qualification in a similar area would be an advantage.

Academic CV

Official academic transcripts
Contact details for two suitable referees
A personal statement (750 words maximum) outlining your suitability for the study, what you hope to achieve from the PhD and your research experience to date.
Any enquiries relating to the project and/or suitability should be directed to Dr Saunders at the address above. Deadline for applications: Friday 21 February 2014.

LINK: http://www.jobs.ac.uk/job/AIB308/phd-studentship-in-skin-immune-cell-interactions-in-health-and-disease/

Clinical Research PhD Fellowship
University of Edinburgh -Centre for Cancer Research

£31,838 – £47,175

Funded by a Cancer Research UK Fellowship, this post provides doctoral training in an internationally renowned research environment in the MRC Centre for Reproductive Health (adjacent to the Royal Infirmary of Edinburgh). The Fellow will work on a project focussing on strategies for early diagnosis and treatment of endometrial cancer addressing key research questions. The post is funded for 3 years leading to a PhD. Appointees will be highly motivated clinicians with an interest in pursuing an academic career. Possession of necessary clinical qualifications to enter a specialist training programme in their chosen medical speciality is essential. Research experience is desirable, but not essential.

Informal enquiries to Professor Philippa Saunders: p.saunders@ed.ac.uk.

Closing Date: 3 March 2014

LINK: http://www.jobs.ac.uk/job/AIB238/clinical-research-phd-fellowship/

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New Grants!

Societá Italiana di Patologia e Medicina Traslazionale (SIPMeT)
 

To promote the entry of young scientists into the mainstream of the basic science community and to encourage the participation of young investigative pathologists in the ASIP Annual Meeting, the Società Italiana di Patologia e Medicina Traslazionale (SIPMeT) is offering a limited number of Young Investigator Awards of $(Euro)600 to offset travel expenses for SIPMeT members to attend the Experimental Biology Meeting.

The ASIP Program Committee will select the recipients based on excellence of the scientific abstracts.  Abstracts will be selected for presentation in either poster sessions or in minisymposia.  These abstracts must be submitted to ASIP topic categories. Members of the SIPMeT who are age 40 years or younger and who submit an abstract to the meeting are eligible to apply for the SIPMeT Young Investigator Award.

Deadline to submit late-breaking abstracts and Young Investigator Award applications is February 21, 2014.

Consortium for Affordable Medical Technologies Innovation Awards Program

CAMTech’s $100K Innovation Awards program is a request for proposals for innovative health technologies targeting pressing global health challenges. The awards look not only for innovative technical solutions, but also for solutions that will be sustainable and scalable in LMICs in the long term.

With support from the Bacca Foundation and the Omidyar Network, we are pleased to announce the next round of Innovation Awards to accelerate innovative technologies to improve health outcomes in low- and middle-income countries. We are initially requesting a one-page letter of intent (LOI) due February 13, 2014 followed by a full proposal for those invited to apply.

The awards provide US$100,000 for one-year of support for innovative technologies. Technologies are defined as devices and protocols, but excluding medicines and vaccines. CAMTech is agnostic to where the technology is in the product development process (e.g. prototyping, field-testing, market research for commercialization etc.) as long as the budget reflects the scope of work proposed.

CAMTech is looking for technologies that can strengthen the delivery of healthcare. Successful proposals demonstrate the applicant’s technology will improve health outcomes specifically in LMICs; incorporate the value of co-creation throughout the process; have an interdisciplinary team with partners from LMICs; identify a business strategy that is sustainable; and be technologically feasible and innovative compared to what is currently available.

Innovation Awards are provided to a range of recipients, including academic researchers, clinicians, engineers and business students, as well as for-profit institutions and NGOs. During the proposal development process, CAMTech urges applicants to contact the CAMTech team to ensure proposals meet all of the identified criteria. For example, proposals that include one of our LMIC partners in Uganda and/or India are preferred in order to enhance the CAMTech network and build capacity at our international sites. Proposals are submitted to CAMTech’s online platform – CoLab.

link: http://www.massgeneralcenterforglobalhealth.org/programs/camtech/innovation-awards/
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Upcoming Microscopy workshops and courses

FLIM workshop 2014

March 27-28, 2014

LCAM (van Leeuwenhoek Centre of Advanced Microscopy), Amsterdam, The Netherlands

Organization: Lambert Instruments, Nikon Instruments Europe

Event website: http://www.lambertinstruments.com/events/events/eventsbycategory/-

Flyer: http://www.eurmicsoc.org/events/Flyer-FLIM-workshop-2014.pdf

 

The Big Freeze: A Course in Cryo Techniques for Electron Microscopy

April 6-11, 2014

Rothamsted Research, Harpenden, UK

Organization: Royal Microscopical Society (RMS)

Event website: http://www.rms.org.uk/events/Forthcoming_Events/bigfreeze

Flyer: http://www.eurmicsoc.org/events/The-Big-Freeze_6-11April2013.pdf

 

 

AFM Workshop Atomic Force Microscopy Applications Workshop

July 21-25, 2014

Liquid Crystal Institute, Kent State University, Kent, Ohio, USA

http://afmworkshop.com/images/BB_Applications%20Wkshop%202_2014.pdf

 

 

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Bladder Cancer Research Innovation Award

BCAN is pleased to announce this new award, supported by the James Family Foundation, in conjunction with Partner Fund Management, which will support the work of one investigator with an exceptionally novel and creative project with great potential to produce a breakthrough in the management of bladder cancer.  The Innovation Award will fund $300,000 over two years.  Applicants may apply for one award – the Young Investigator Award or the Innovation Research Award.

The aim of the 2014 Bladder Cancer Research Innovation Award is to support exceptionally novel and creative projects with great potential to produce breakthroughs in the management of bladder cancer.  Proposals will be accepted for creative ideas and innovative approaches that have direct application and relevance to bladder cancer.

“There have been so many advances in the cancer arena.  With this Innovation Award, we hope to bring new perspectives and forward-thinking ideas to bladder cancer research,” stated Chris James of the James Family Foundation and Partner Fund Management.  “This is the sixth most diagnosed cancer in the U.S., yet there have been no significant advances in the disease in more than 20 years.  We are hopeful that this research award will move us in the right direction.”

The 2014 Bladder Cancer Research Innovation Award will complement BCAN’s 2014 Young Investigator Awards, generously supported by The JPB Foundation.

Link: http://www.bcan.org/research/grants/bladder-cancer-research-innovation-award/